I'm kind of hardcore into NOT using pharms for managing basic body chemistry (for example, cholesterol). I hate the fact that way too many physicians are way too quick to script the "drug of the week".
However I think there are people who have a - by definition, disease - that may present itself as less than desirable psycho-social characteristics. They may not be able to just "get over it". Pharms may be the only way.
Illegal narcotics? The *illegal* part is just overrides my sensibilities too much, so I don't ever consider pursuing them.