Think about real life, pick up a ball and spin the opposite way without breaking your wrist. If you bowl the correct way, you should not notice this at all. (For instance, right handed person hitting a 10 pin by standing left all the way, aiming at the gutter and spinning to the left) There should never be any situation in the game where you change your actual throw, just the direction.
For people who can't bowl straight, STOP TRYING, your probably better than you would be anyway.
</rant from a varsity bowler>