IGN's interview with the No More Heroes developer revealed that the main character is on a mission to become the #1 ranked assassin. The game is gonna be a free-roaming shooter, as well. However, there were no bits of info on possible multiplayer modes.
I got to thinking about it, and I think it would be awesome if you and a couple of your friends were spawned at seperate locations on the map, around a 'target' (say, a drug trafficker); the goal would be to be the first (and only, obviously) to assassinate the guy. Somewhere along the lines of Smokin' Aces, it seems. I'd like to see that movie....
But anyways, I sent Cassamassina (IGN Wii Editor) a message asking for his knowledge on the subject. What about your thoughts?
Of course, it'd all be best online.