You beat me to it, i was going to post about eyeshield 21
From what i've seen, its cellshaded and i don't think You play full american football games but I'm not sure. It's based on the ds game: eyeshield 21: max devil power. Its more manga then madden. The game is now mission based and follows the team 'the devil bats'.
I read in N.Revolution that the controls are:
flick the remote left,right,up or down to dodge incoming tackles, shake it rapidly when defending, the the cursor when throwing and target the ball while catching. The B-button activates special moves, while waggling at the precisely the right time will provide the perfect punt.