Although I've never had Nintendo DS, Second Opinion is basically the same with DS version with better graphic and Wii controller.Originally Posted by Wozz500
I don't know much about it, but there's 2-player cooperative mode in the New Blood! I've always wanted this since I first bought Second Opinion, and now my dream's coming true..
And I heard it's setting is 10 years after the Second Opinion. Also new virus instead of GUILT. New characters, new surgeries, oh and also there is a ranking of operation score with others through online.