I don't think it'd work.
For one, using a stylus and using a wiimote are two completely different things.
The stylus offers excellent support. I couldn't begin to fathom playing a game like Elite Beat Agents with a wiimote!
Also, the buttons would feel too odd.
The placement would be off.
It would need the Classic controller to work buttons right.
But then you lose the wiimote as a stylus.