i would say mario kart. but at first. i hated it. i hated the wheel. Then I started using the gamecube controller. then i loved it
so the one game i LOVED from when i first started playing was prob gh world tour OR super mario sluggers.
prob sluggers cause i had already played GH before world tour
and for your big games question there is obviously mario kart, super mario galaxy, zelda twilight princess. guitar hero
those are the only ones that pop off the top of my head :]