A smoke-filled room is not a "normal environment".
As you have already been told: normal dust is easily cleaned out, and is at a much-lower level than smoke particulates. Smoke residue, on the other hand, is not only more-prevalent in the air but is extremely sticky and does not just blow out or dust off.
If smoke and dust were equal, then non-smokers' lungs would look the same as smokers' lungs, from all the dust in the air. That is not the case.
Go off the deep end much? That's hardly what I said or suggested. You asked if smoking was bad for the Wii. It is. Covering it is also bad, as it needs to draw fresh air through itself to stay cool.
We're trying to help. If you don't want the truth and are just going to exaggerate when you hear it, then don't ask the question. Obviously you care more about smoking than your Wii and would only accept "hey, go ahead! It's fine!" to justify smoking, so do what you'd like. Like I said, it's your nickle.