Never got into Earthbound, thought it overrated! But Shadowrun was a different league, how it got released on a Nintendo console back then is amazing considering how adult it is, and without it I don't think anyone would've made the Deus Ex games which IMO are possibly the best games ever made. Apart from the aformentioned Secret of Mana of course, which I don't think will ever be beaten if you take into account all genres, it truly had everything, and still does.